Which statement about agenesis of the corpus callosum is true?

Which statement about agenesis of the corpus callosum is true?

• A. It is always associated with severe motor deficits
• B. It never affects cognitive function
• C. It is easily repaired surgically
• D. It can be associated with developmental disorders and variable cognitive outcomes

Answer: (D)

Agenesis of the corpus callosum shows a wide range of outcomes because the loss of the main bridge between the brain’s hemispheres disrupts interhemispheric communication, yet the brain often finds ways to adapt through other pathways. This means cognition and development aren’t fixed—some individuals develop with typical or near-typical intelligence, while others experience developmental delays, learning challenges, or features seen in neurodevelopmental disorders. Motor problems aren’t universal either; you can see individuals with ACC who have no major motor deficits and others who have coordination or fine-motor issues. There is no surgical repair to recreate the corpus callosum, so management focuses on supportive therapies and education rather than a cure. Therefore, the statement that ACC can be associated with developmental disorders and variable cognitive outcomes is true.

Agenesis of the corpus callosum shows a wide range of outcomes because the loss of the main bridge between the brain’s hemispheres disrupts interhemispheric communication, yet the brain often finds ways to adapt through other pathways. This means cognition and development aren’t fixed—some individuals develop with typical or near-typical intelligence, while others experience developmental delays, learning challenges, or features seen in neurodevelopmental disorders. Motor problems aren’t universal either; you can see individuals with ACC who have no major motor deficits and others who have coordination or fine-motor issues. There is no surgical repair to recreate the corpus callosum, so management focuses on supportive therapies and education rather than a cure. Therefore, the statement that ACC can be associated with developmental disorders and variable cognitive outcomes is true.