Which processes continue postnatally to refine CNS circuitry?

Which processes continue postnatally to refine CNS circuitry?

• A. Synaptogenesis and myelination
• B. Neurogenesis only
• C. Gliosis and demyelination
• D. Synaptogenesis only

Answer: (A)

The idea being tested is that brain maturation after birth involves both forming new connections and increasing the insulation of those connections to fine‑tune how circuits work. Synaptogenesis continues after birth, with experiences shaping which synapses are strengthened and which are pruned away, helping networks become more efficient. At the same time, myelination of axons keeps progressing, speeding up signal transmission and improving timing across neural networks. Together, these ongoing processes refine CNS circuitry as a child grows. Neurogenesis does occur in some limited regions, but it doesn’t drive widespread postnatal refinement the way synaptogenesis and myelination do. Gliosis and demyelination are not normal maturation processes.

The idea being tested is that brain maturation after birth involves both forming new connections and increasing the insulation of those connections to fine‑tune how circuits work. Synaptogenesis continues after birth, with experiences shaping which synapses are strengthened and which are pruned away, helping networks become more efficient. At the same time, myelination of axons keeps progressing, speeding up signal transmission and improving timing across neural networks. Together, these ongoing processes refine CNS circuitry as a child grows. Neurogenesis does occur in some limited regions, but it doesn’t drive widespread postnatal refinement the way synaptogenesis and myelination do. Gliosis and demyelination are not normal maturation processes.