The ganglionic eminences contribute interneurons to the cortex via which migration mode?

The ganglionic eminences contribute interneurons to the cortex via which migration mode?

• A. Radial migration
• B. Tangential migration
• C. Lateral migration
• D. Apical migration

Answer: (B)

Interneurons that populate the cortex come from the ganglionic eminences in the ventral forebrain and travel tangentially. This means they move parallel to the surface of the brain, crossing from ventral regions into the developing cortex rather than moving straight outward from the ventricular zone. Once they reach the cortical region, they integrate and settle into appropriate layers, often then moving within the cortex along other paths as needed. This tangential route is distinct from how many excitatory cortical neurons reach the cortex, which is via radial migration along radial glia from the ventricular zone to the cortical plate.

Interneurons that populate the cortex come from the ganglionic eminences in the ventral forebrain and travel tangentially. This means they move parallel to the surface of the brain, crossing from ventral regions into the developing cortex rather than moving straight outward from the ventricular zone. Once they reach the cortical region, they integrate and settle into appropriate layers, often then moving within the cortex along other paths as needed. This tangential route is distinct from how many excitatory cortical neurons reach the cortex, which is via radial migration along radial glia from the ventricular zone to the cortical plate.