Dorsal root ganglia originate from which embryonic tissue?

Dorsal root ganglia originate from which embryonic tissue?

• A. Neural crest cells
• B. Neural tube
• C. Endoderm
• D. Mesoderm

Answer: (A)

Dorsal root ganglia originate from neural crest cells. These cells arise at the border between the neural plate and the non-neural ectoderm during neurulation and then migrate to form many components of the peripheral nervous system, including the sensory neuron cell bodies that reside in the dorsal root ganglia. This multipotent population also gives rise to Schwann cells and other peripheral structures, which is why DRG are part of the peripheral nervous system. The neural tube forms the central nervous system, while endoderm and mesoderm give rise to internal organs and musculoskeletal tissues, respectively, not to DRG.

Dorsal root ganglia originate from neural crest cells. These cells arise at the border between the neural plate and the non-neural ectoderm during neurulation and then migrate to form many components of the peripheral nervous system, including the sensory neuron cell bodies that reside in the dorsal root ganglia. This multipotent population also gives rise to Schwann cells and other peripheral structures, which is why DRG are part of the peripheral nervous system. The neural tube forms the central nervous system, while endoderm and mesoderm give rise to internal organs and musculoskeletal tissues, respectively, not to DRG.